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|Title:||Comparison of mortality in Asbest city and the Sverdlovsk region in the Russian Federation: 1997–2010|
|Authors:||Kovalevskiy EV; Schonfeld SJ; Feletto E; Moissonnier M; Kashanskiy SV; Bukhtiyarov IV; Schüz J|
|Categories:||Cancer Control, Survivorship, and Outcomes Research - Surveillance|
|Journal Title:||Environmental Health|
|Abstract:||Background The Sverdlovsk region of the Russian Federation is characterised by its abundance of natural resources and industries. Located in this region, Asbest city is situated next to one of the largest open-pit chrysotile asbestos mines currently operational; many city residents are employed in activities related to mining and processing of chrysotile. We compared mortality rates from 1997 to 2010 in Asbest city to the remaining Sverdlovsk region, with additional analyses conducted for site-specific cancer mortality. Methods Population and mortality data for Asbest city and Sverdlovsk region were used to estimate crude and age-specific rates by gender for the entire period and for each calendar year. Age-standardized mortality rates were also calculated for the adult population (20+) and Poisson regression was used to estimate standardized mortality ratios, overall and by gender. Results During the period of 1997 to 2010, there were similar mortality rates overall in Asbest and the Sverdlovsk region. However, there were higher rates of cancer mortality (18 % males; 21 % females) and digestive diseases (21 % males; 40 % females) in Asbest and lower rates of unknown/ill-defined in Asbest (60 % males; 47 % females). Circulatory disease mortality was slightly lower in Asbest. Cancer mortality was higher for men in Asbest from oesophageal, urinary tract and lung cancers compared to the Sverdlovsk region. In women, cancer mortality was higher for women in Asbest from stomach, colon, lung and breast cancers compared to the Sverdlovsk region. Conclusions This large population-based analysis indicates interesting differences but studies with individual exposure information are needed to understand the underlying factors.|
|Division:||Cancer Research Division|
|Funding Body:||This study is funded by the Ministry of Health of the Russian Federation in the framework of the Federal target programme “National System of Chemical and Biological Safety of the Russian Federation (2009–2014)” under a general framework of action between the Federal state budgetary scientific institution “Scientific Research Institute of Occupational Health” and the International Agency for Research on Cancer (IARC). EF’s work is being undertaken during the tenure of an IARC-Australia Postdoctoral Fellowship from the International Agency for Research on Cancer, supported by Cancer Council Australia (CCA).|
|Appears in Collections:||Research Articles|
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