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Title: Describing Patterns of Care in Pancreatic Cancer: A Population-Based Study
Authors: Burmeister EA; O'Connell DL; Beesley VL; Goldstein D; Gooden H; Janda M; Jordan SL; Merrett ND; Payne ME; Wyld D; Neale RE
Categories: Cancer Type - Pancreatic Cancer
Cancer Control, Survivorship, and Outcomes Research - Health Services, Economic and Health Policy Analyses
Year: 2015
Journal Title: Pancreas
Volume: 44
Issue: 8
Page number start: 1259
Page number end: 1265
Abstract: OBJECTIVES: Despite pancreatic cancer being the fifth highest cause of cancer death in developed regions, there is a paucity of population-based management details for patients with pancreatic cancer. The objective of this study was to reflect on current practice and outcomes to facilitate future improvement. METHODS: A comprehensive population-based patterns-of-care study in 2 Australian states was conducted. Patients diagnosed with pancreatic adenocarcinoma between July 2009 and June 2011 were identified by cancer registries, and detailed clinical data were collected from medical records. RESULTS: Data were collected for 1863 patients, 96% of those eligible. The majority resided in major cities; their median age was 72 years, and 54% were men. Over half of the cases (58%) had metastatic disease at diagnosis. Resection was attempted for 20% of patients but only completed in 15%. The uptake of adjuvant chemotherapy (76%) and the proportion alive at 1-year (22%) were higher than reported in previous population-based reports. Of those with no complete surgical resection, 43% received palliative chemotherapy. CONCLUSIONS: This population-based overview of the management of patients with pancreatic cancer suggests that, despite evidence that the proportion surviving and the use of adjuvant chemotherapy has increased, there may still be underutilization of cancer-directed therapies.
Division: Cancer Research Division
Funding Body: This study was funded by a National Health and Medical Research Council (Australia) project grant (#613654). R.E.N. is funded by a senior research fellowship, S.J.J. by a career development fellowship, and E.A.B. by a doctoral scholarship, all from the National Health and Medical Research Council.
DOI: 10.1097/MPA.0000000000000384
Appears in Collections:Research Articles

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