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dc.contributor.authorNilssen Yen
dc.contributor.authorStrand TEen
dc.contributor.authorWiik Ren
dc.contributor.authorBakken IJen
dc.contributor.authorYu XQen
dc.contributor.authorO'Connell DLen
dc.contributor.authorMøller Ben
dc.date.accessioned2015-02-17T09:41:41Zen
dc.date.available2015-02-17T09:41:41Zen
dc.date.issued2014en
dc.identifier.govdoc2075en
dc.identifier.urihttp://researchpubs.cancercouncil.com.au/cancercounciljspui/handle/1/1618en
dc.description.abstractOBJECTIVE: To construct an updated comorbidity index (Patient Register Index [PRI]) using national data collections from Norway and compare its predictive ability of 1-year mortality with the Charlson Comorbidity Index (CCI). MATERIALS AND METHODS: Data regarding over 1.11 million patients registered in the Norwegian Patient Register in 2010 and 2011 were used to construct the PRI. The PRI was evaluated by comparing its model fit and discrimination with the CCI. RESULTS: Compared with the CCI, the PRI weights decreased for six, increased for four, and were unchanged for seven diseases. When the PRI was added to the model including age and sex, the age effects were reduced by up to 38% for patients older than 50 years. All measures of model fit improved for the PRI model. CONCLUSION: Adjustment for comorbidity is especially important for patients 50 years of age or older, and its effect on 1-year mortality is almost comparable to the age effect. The PRI is based on more recent data than the CCI, and is more representative of the general population due to its constructionen
dc.language.isoenen
dc.subject.otherEtiology - Resources and Infrastructureen
dc.subject.otherCancer Control, Survivorship, and Outcomes Research - Resources and Infrastructureen
dc.titleUtilizing national patient-register data to control for comorbidity in prognostic studiesen
dc.typePeer Reviewed Journal Articleen
dc.subject.keywordsAustraliaen
dc.subject.keywordsPublic Healthen
dc.subject.keywordsRegistriesen
dc.subject.keywordsResearchen
dc.subject.keywordsWalesen
dc.subject.keywordscanceren
dc.subject.keywordscancer registryen
dc.subject.keywordsComorbidityen
dc.subject.keywordsData Collectionen
dc.subject.keywordsmethodsen
dc.subject.keywordsmortalityen
dc.subject.keywordsNew South Walesen
dc.subject.keywordsNorwayen
dc.identifier.journaltitleClinical Epidemiologyen
dc.identifier.volume6en
dc.identifier.pagestart395en
dc.identifier.pageend404en
dc.identifier.programmeHealth Services Researchen
dc.identifier.doi10.2147/CLEP.S70742en
dc.identifier.doiclep-6-395en
dc.identifier.divisionCancer Research Division-
Appears in Collections:Research Articles

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