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Title: Geographic variation in prostate cancer survival in New South Wales
Authors: Yu XQ
Luo Q
Smith DP
O'Connell DL
Baade PD
Categories: Cancer Type - Prostate Cancer
Diagnosis & Treatment - Geographic differences
Population Groups - Men's Health
Population Groups - NSW Only
Keywords: analysis; regional; Research; Risk; survival; Survival Analysis; Survival Rate; trends; Wales; Australia; cancer; cancer survival; Design; mortality; New South Wales; Other; prostate
Pub. Date: 2014
Journal Title: Med J Aust
Volume: 200
Issue: 10
Page number start: 586
Page number end: 590
Abstract: OBJECTIVES: To determine whether the previously reported urban-rural differential in prostate cancer survival remains after adjusting for demographic and clinical factors, and to investigate temporal trends in this differential. DESIGN, SETTING AND PARTICIPANTS: Retrospective population-based survival analysis of 68 686 men diagnosed with prostate cancer from January 1982 to December 2007 in New South Wales. MAIN OUTCOME MEASURES: Survival rate and relative excess risk (RER) of death over 10 years of follow-up in relation to geographic remoteness after adjusting for other prognostic factors. RESULTS: Overall, 10-year survival increased during the study period, increasing from 57.5% in 1992-1996 and 75.7% in 1997-2001 to 83.7% in 2002-2007. The increasing trends were also observed across categories of geographic remoteness and socioeconomic status. Urban-rural differentials were significant (P < 0.001) after adjusting for five important prognostic factors, with men living outside major cities having higher risk of death from prostate cancer (RER, 1.18 and 1.32 for inner regional and rural areas, respectively). Socioeconomic status was also a significant factor (P < 0.001) for prostate cancer mortality, with the risk of dying being 34% to 40% higher for men living in socioeconomically disadvantaged areas than those living in least disadvantaged areas. There was no evidence that this inequality is reducing over time, particularly for men living in inner regional areas. CONCLUSIONS: Despite the increasing awareness of urban-rural differentials in cancer outcomes, little progress has been made. Appropriately detailed data, including details of tumour characteristics, treatment and comorbid conditions, to help understand why these inequalities exist are required urgently so interventions and policy changes can be guided by appropriate evidence
Programme: Health Services Research
Division: Cancer Research Division
DOI: 10.5694/mja13.11134
URI: http://researchpubs.cancercouncil.com.au/cancercounciljspui/handle/1/1609
Appears in Collections:Research Articles

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